MARK3's Canal Prep, Root Canal Preparation Cream is formulated with urea-peroxide 10% and ethylene diamine tetra acetic (EDTA) acid 15% in a special water-soluble base, which lubricates the canal for the introduction of files, and reduces possible file separation. When used with sodium hypochlorite, the chemical action boosts the dissolution of organic tissue and also helps remove the smear layer.